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We are using interdisciplinary approaches ranging from biophysics, biochemistry and cellular and molecular biology to rein vivo models and life imaging.
We are the new, modern Munich driving school for Schwabing and Maxvorstadt. On three evenings a week, ur fully-equipped driving school will give you the opportunity to become familiar with the theory – quickly and thoroughly.
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Together with an interdiziplinary Mannschaft he uncovered the molecular mechanisms of Alzheimer's disease and identified target molecules for therapeutic treatment.
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Inhibition of secretases as a therapeutic approach requires detailed knowledge about the physiological functions and biochemical properties of these enzymes to avoid unwanted side effects. Christian Haass was the first to demonstrate a physiological function for beta-secretase. He showed that this protease is critically required for the regulation of myelination. Furthermore, he identified a novel APP processing pathway, which was overlooked for more than 20 years and which has strong implications for clinical trials using beta-secretase inhibitors. He was also the first to identify the highly complicated subunit composition of gamma-secretase. All these findings not only helped to understand several signaling pathways critically involved rein brain development (such as myelination and cell differentiation) but also provided the Stützpunkt for several current therapeutic approaches.
You are allowed to have 10 minus points. You have failed the test if you get 11 or more negativ points. If you incorrectly answer two questions each with five negativ points, you have also failed the test rein spite of not exceeding the maximum number of negativ points; hinein Class B, questions with 5 points have a greater relevance hinein the theoretical test.
Haass was awarded the Hector Science Award and is currently leading a major project on the clinical testing of an Alzheimer's antibody.
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We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of Hier ur research.